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农村地区艾滋病抗病毒治疗的直接成本分析 被引量:8

Direct Cost Analysis of Therapy on HIV-1 Infection in Rural Area of China
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摘要 目的:估算我国综合性艾滋病研究项目(China integrated program for research on AIDS,China,CIPRA)临床治疗的直接成本,为在我国农村地区推行艾滋病(HIV/AIDS)高效抗逆转录病毒治疗(Highly Active Anti-retroviral therapy,HAART)提供卫生经济学方面的参考依据。方法:收集治疗的成本资料,根据当地的医疗服务价格水平,估算包括抗病毒药品费用、随访检查费用及不良事件(adverse event,AE)处理费用的直接成本。结果:治疗1年期间,100例患者因不良事件平均每人住院为3.5天,每人门诊治疗为3.6次,平均每日住院费用和每次门诊费用分别为186.8元和43.0元。每人治疗总费用为26521.3元,其中抗病毒药品费用占67.0%,有效性监测费用占26.4%,安全性监测费用占3.5%,不良事件处理费用占3.0%,处理不良事件的费用约占当地农民人年均收入的30.0%。结论:按本方案在中国中西部农村地区以县级医疗机构为基点开展HAART治疗,每人每年的直接成本约为26500.0元,安全性监测费用占总费用比例较小,是为保证HAART治疗安全必须优先投入的部分。不良事件处理费用成为当地HIV/AIDS患者的重要经济负担,需要相应的补偿机制予以分担。 Objectives To estimate the direct cost of therapy aeeording to HIV/AIDS China CIPRA P4 regimens, and to supply referential data on health economy in planning the national HAART in rural areas. Method The treatment cost data, including laboratory test, prescription and hospitalization was calculated to estimate the direct costs of HAART according to the local practice priee, including antiretroviral drug, laboratory test and AE treatment. Results During one year treatment period, 100 subjects had 3.5 mean inpatient days and 3.6 mean outpatient visits. The average inpatient cost was 186.8 Yuan per day and the average outpatient cost was 43.0 Yuan per visit. According the protocol, the direct cost is 26 521.3 Yuan per patient year, with 67.0% fur antiretruviral drugs, 26.4% for efficacy monitoring, 3.5% for safety monitoring and 3.0% fur AE treatment. Cost for AE treatment is about 30.0% of each farmer's net income per year. Conclusion If HAART is performed on district hospital in rural areas of center-west provinces, the direct cost will be about 26 500 per person-year, safety lab monitoring cost accounts a small pereentage of the total cost and is essential to insure the safety of therapy. Cost of treating AE will be a great eeonomic tmrden tbr HIV patients, subsidiary programs must be developed to share the patients' burden.
出处 《中国卫生经济》 2008年第10期39-41,共3页 Chinese Health Economics
基金 中国综合性艾滋病研究项目(ChinaCIPRA U19AI1915)。
关键词 艾滋病 高效抗逆转录病毒治疗 直接成本 HIV/AIDS, highly active antiretroviral therapy, direct cost
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参考文献12

  • 1曹韵贞.艾滋病的临床与基础研究进展[J].中国医学科学院学报,2006,28(5):609-612. 被引量:3
  • 2张福杰,文毅,于兰,马烨,潘捷,赵燕.艾滋病的抗病毒治疗与我国的免费治疗现状[J].科技导报,2005,23(7):24-29. 被引量:105
  • 3WHO, UNAIDS. Global access to HIV therapy tripled in two years, but significant challenges remain. Press release. March 2006.
  • 4Rlevy A, James D, Johnstom KM, et al. The direet costs of HIV/ AIDS care[J]. Lancet Infectious Disease, 2006, 6(3): 171-177.
  • 5Beck EJ, Mandalia S, Gaudreault M, et al. The cost-effectiveness of highly active antiretroviral therapy, Canada 1991-2001[J]. AIDS, 2004. 18(18): 2 411-2 418.
  • 6中华人民共和国卫生部.UNAIDS.WHO.2005年中国艾滋病疫情与防治工作进展报告[R].2006-01.
  • 7Chen RY, Aecortt NA, Westfall AO, et al. Distribution of health care expenditures for HIV-infeeted patients [J].Clin Infect Dis, 2006, 42 (7):1 003-1 010.
  • 8刘中夫,梅志强,郑锡文,张文吉,王凤香,周郁,毛宇嵘,曲淑霞.对我国中部某省三起非法地下采集血浆案艾滋病病毒感染情况调查[J].中华流行病学杂志,2000,21(6):466-467. 被引量:7
  • 9王鋆,张钧.药物经济学成本-效果分析[J].药学实践杂志,1995,13(4):193-197. 被引量:462
  • 10Bozzette SA, Joyce G, Mccaffrey DF, et al. Expenditures for the care of HIV-infected patients in the era of highly active antiretroviral therapy[J]. N Engl J Med, 2001, 344(11): 817-823.

二级参考文献39

  • 1张钧,郭震洲,王立强,任守英.药物经济学概述及在我国运用的几点设想[J].中国药房,1993,4(5):11-13. 被引量:94
  • 2阎依群.利用药品的成本效益分析减少药品消耗[J].中国药房,1994,5(3):6-7. 被引量:5
  • 3张钧.药物经济学概论[J].药学实践杂志,1995,13(1):3-6. 被引量:79
  • 4Carmona A, Knobel H, Guelar A, et al. Factors influencing survival in HIV infected patients treated with HAART [C]. 13th International AIDS Conference. Durban, South Africa. 2000.(Abstract TuOrB417)
  • 5Walsh J C, Hertogs K, Gazzard B. Viral drug resistance,adherence and pharmacokinetic indices in HIV-1 infected patients on successful and failing protease inhibitor based HAART [C]. 40th Interscience Conference of Antimicrobial Agents and Chemotherapy. Toronto, Canada. 2000. (Abstract 699)
  • 6Arnsten J, Demas P, Gourevitch M, et al. Adherence and viral load in HIV-infected drug users: comparison of self-report and medication events monitors [C]. 7th Conference on Retroviruses and Opportunistic Infections. San Francisco, CA, 2000. (Abstract 69)
  • 7Max B, Sherer R. Management of the adverse effects of antiretroviral therapy and medication adherence [J]. Clin. Infect.Dis., 2000, 30 (1 2): 96~116
  • 8Shapiro M F, Morton S C, McCaffrey D F, et al. Variations in the care of HIV-infected adults in the United States: Results from the HIV Cost and Services Utilization Study[J]. J. Am. Med.Assoc., 1999, 281(24): 2 305~2 315
  • 9Chesney MA. Factors affecting adherence to antiretroviral therapy[J]. Clin. Infect Dis., 2000,30 ( 1 2 ): 171 ~ 176
  • 10张福杰.国家免费艾滋病抗病毒药物治疗手册[M].北京:人民卫生出版社,2005.71-72.

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