普米克令舒雾化吸入辅助治疗小儿毛细支气管炎临床疗效观察

Clinical Observation of the Effect of Pulmicort Respules Inhalation in the Treatment of Children Bronchiolitis

目的探讨普米克令舒辅助治疗毛细支气管炎的疗效及安全性。方法2003年2月—2007年2月，内蒙古医学院附属人民医院收治的85例毛细支气管炎患儿，分为治疗组和对照组。2组均采用综合治疗（抗感染、抗病毒、吸氧、镇静、补液等）；治疗组加用普米克令舒雾化吸入治疗。用法为每次1ml（含布地奈德0．5mg），加生理盐水二三毫升，由空气压缩泵雾化吸入，每日2次，每次吸入10～15min，疗程为5～7d。对2组咳嗽、呼吸困难、肺部啰音消失时间、平均治疗天数进行对照评价。结果治疗组治愈率明显提高，肺部啰音、咳嗽消失时间及住院时间明显缩短，与对照组比较，差异有统计学意义（P〈0．05或P〈0．01）。结论在常规治疗的基础上加用普米克令舒雾化吸入，可明显缩短病程，提高治愈率，疗效确切，使用安全。

[Objective] To explore the therapeutic effect and safety of Pulmicort Respules inhalation in the treatment of ehildren bronchiolitis. [ Methods] 85 cases of children bronchiolitis collected between February of 2003 and February of 2007 were divided into two groups, namely the treatment group and the control; both groups were treated with integrated therapy （ antibiotics, antivirus, oxygen inhalation, calmness, rehydration, et al ） , the control group were assisted with Pulmieort Respules inhalation, 1 ml （ containing 0.5mg Budesonide） for 10 - 15 minutes per time, combined with 2 -3ml N. S driven for inhalation by air bump, Bid for a period of 5 -7 days; comparison was made on the coughing, dyspnea, lung rale missing and the average treatment days. [ Results] The cure rate of the control increased significantly ; lung rale and coughing missing and the hospitalization period were obviously shorter than that of the control, the difference was significant （P 〈0. 05 or P 〈0. 01 ）. [ Conclusion]To add Pulmieort Respules inhalation into the treatment of children bronchiolitis based on the routine therapy can significantly shorten the period and improve the cure rate accurately and safely.