飞蓬的化学成分研究

Studies on the Constituents from the Herba of Erigeron acer

目的：研究飞蓬（Erigeron acerL.）全草的化学成分。方法：应用硅胶柱色谱法及制备型硅胶薄层色谱对其化学成分进行分离,并利用^13C-NMR,^1H-NMR和MS等方法鉴定分离得到的化合物。结果：从飞蓬的干燥全草中分离得到5个化合物,分别鉴定为α-香树脂醇（1）、β-香树脂醇（2）、咖啡酸（3）、槲皮素（4）、4′-羟基黄芩素-7-O-β-D-葡萄糖醛酸苷（5）。结论：该5个化合物均为首次从飞蓬中分离得到。根据DEPT、HMQC、HMBC谱对化合物（5）的碳信号重新进行了归属,同时根据HMBC、HMQC、^1H-^1HCOSY谱首次归属了该化合物葡萄糖醛酸部分的2″-5-″H的信号。

Objective ： To investigate the chemical constituents of the aerial part of Erigeron acer. Methods ： The chemical constituents were isolated by various columns and thin layer chromatographic methods. The structures were identified by spectral data. Results ： Five compounds were isolated and identified as α-amyrin（ 1 ）,β-amyrin（ 2 ）, caffeie acid （3）, quercetin（4 ）, 4′-hydroxywogonin-7-O-β-D-glucuronic acid glycoside（5 ）. Conclusion： The five compounds are obtained from this plant for the first time. The signals of ^13 C- NMR of the compound （5） are reassigned by means of DEPT,HMQC ,HMBC, the signals of ^1H-NMR of 2＂ -5＂-H of the glucuronie acid moiety are assigned by means of HMBC,HMQC、 ^1H^1H COSY for the first time.