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混合淋巴细胞反应中白细胞介素-2和肿瘤坏死因子-α的表达对肝移植急性排斥反应的预测价值

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摘要 白细胞介素(IL)-2和肿瘤坏死因子(TNF)-α的表达水平与器官移植供受体间主要组织相容复合体(MHC)的吻合度密切相关。动物实验叫和临床病例中,移植物受体术后血浆IL-2或TNF-α浓度升高提示急性排斥反应(AR)的发生。淋巴细胞激活是肝脏移植AR的首要因素,供受体淋巴细胞混合反应(MLR)是研究移植排斥反应机制的可靠模型。
出处 《中华实验外科杂志》 CAS CSCD 北大核心 2008年第10期1343-1343,共1页 Chinese Journal of Experimental Surgery
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