正常高值血压人群血清C反应蛋白水平分析

Analysis of C Reactive Protein Level in the Crowd with Prehypertensive

目的观察正常高值血压人群血清C反应蛋白(CRP)水平的变化,探讨炎症与高血压发生的关系。方法采用酶联免疫吸附法(ELISA)分别检测正常血压组(120例)、正常高值血压组(132例)和高血压组(124例)血清CRP水平。结果正常高值血压组CRP水平(3.25±1.43 mg/L)显著高于正常血压组(2.16±0.97 mg/L,P<0.01);高血压组(4.52±1.85 mg/L)又显著高于正常高值血压组(P<0.01)。结论CRP在正常高值血压时已开始升高,检测CRP有助于预测高血压的发生。

Objective To observe the change of C reactive protein（CRP） level in the crowd with prehypertensive,and discuss the relationship between inflammation and occurrence of hypertension. Methods Detecting the CRP level in blood serum in normal blood pressure group （120 examples）,prehypertensive group （132 examples） and hypertension group （124 examples） by enzyme linked immunosorbent assay （ELISA）, respectively. Results CRP level in prehypertensive group（3.25±1.43mg/L） was significantly higher than in normal blood pressure group（2.16±0.97 mg/L,P〈0.01） and it in hypertension group （4.52 ± 1.85 mg/L）was significantly higher than prehypertensive group （P〈0. 01）. Conclusion The CRP level had raised in prehypertensive peoples ,so the detection of CRP can forecast the occurrence of hypertensive.