尿微量清蛋白检测在冠心病中的临床意义

Clinical Significance of Microalbuminria Detecting in Patients with Coronary Heart Disease

目的探讨尿微量清蛋白(MA)测定在冠心病(CHD)患者中的临床意义,分析尿微量清蛋白与血清中总胆固醇(TC)、三酰甘油(TG)、高密度脂蛋白(HDL)、低密度脂蛋白(LDL)、空腹血糖(GLU)之间的关系。方法分别测定46例健康人及50例冠心病患者尿中MA含量和血清中TC,TG,HDL,LDL,空腹GLU的水平并且进行比较分析。结果冠心病组尿中微量清蛋白水平明显高于健康对照组(P<0.05),血清TC及LDL水平两组之间亦有显著性差异(P<0.05),并且冠心病患者MA含量与空腹血糖水平密切相关,随着空腹血糖升高而升高。结论尿中MA的含量增加与冠心病发生密切相关,MA不仅是冠心病的危险因素,当其与某些已确立的冠心病危险因素同时出现时,冠心病危险性增加。

Objective To investigate the determination of microalbuminuria in patients with coronary heart disease in the clinical significance of urinary albumin and the relationship between the total cholesterol（TC）,triglyceride （TG）,high density lipoprotein （HDL） ,low density lipoprotein （LDL） ,glucose. Methods 46 cases of healthy people and 50 patients with coronary artery disease patients with the MA content and serum TC, TG,HDL,LDL and the level of fasting GLU a comparative analysis. Results Group of coronary heart disease in urine microalbumin levels were significantly higher than those in healthy control group（P〈0. 05）. MA in patients with coronary artery disease and is closely related to the level of glucose,glucose increased with the increase. Conclusion MA content in urine increased with coronary heart disease are closely related ,MA is not only the risk factors of coronary heart disease ,when it has been established with certain risk factors for coronary heart disease at the same time ,increased risk of coronary heart disease.