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影响唇鳞癌预后的临床病理因素分析

Clinic Pathology Prognostic Factors in Squamous Cell Carcinoma of Lip
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摘要 目的:研究影响唇鳞癌预后的临床病理因素。方法:以各临床病理指标来研究与唇鳞癌预后有关的因素。结果:1.区域淋巴结转移:T1有5.4%,T2有6.5%,T3有41.7%的病例出现区域淋巴结转移(0.01<P<0.025)。高、中、低分化出现淋巴结转移者分别为3.6%、6.7%和66.7%(P<0.005)。出现淋巴结转移者的病理核分裂数为3.25个,明显高于未出现淋巴结转移(P<0.01)。而浸润厚度和微血管数与淋巴结转移无关。2.术后复发:复发组浸润厚度为5.07mm,明显高于无复发组(P<0.05);而且复发组的病理核分裂数也明显高于无复发组。高、中、低分化者出现复发的分别为7.1%、13.3%、55.6%(P<0.005);从淋巴细胞浸润程度来看,两组间无明确关系。结论:肿瘤直径大、分化程度低、病理核分裂数大于3个时,易出现区域淋巴结转移。浸润厚度大于5mm、病理核分裂数大于2个、分化程度低时易出现复发。淋巴细胞浸润程度及微血管数与区域淋巴结转移和复发无关。 Objective:To study clinic pathology prognostic factors in squamous cell carcinoma of lip. Methods: 80 squamous cell carcinoma of lip were analyzed by means of several clinic and pathology factors. And the prognostic factors were showed. Results: 1. There were 5.4% ,6.5% ,41.7%cases showed neck metastasis in T1 ,T2,T3 tumors and 3.6% ,6. 7% ,66.7%in well, middle,poor differentiation tumors respectively. The pathological karyokonesis number was 3.25 in the cases of neck metastasis, and the same time the number showed statistically significant(p〈0.01). 2. The mean thickness of recurrence cases was 5.07mm (p〈0. 05). There were 7.1%, 13.3 %, 55.6% cases showed recurrence in well, middle, and poor differentiation respectively(p〈0. 005). Conclusion: Neck metastasis was significantly associated with large tumor size and poor differentiation. It was easy to occur cervical lymph node spreading when the number of pathological karyokinesis was more than three. Further more, local recurrence was significantly associated with poor differentiaton. It was easy to recur when the tumor thickness was more than 5mm and the number of pathological karyokonesis was more than two. Both the number of cap illary and the invasion degree of lymph cell were not the related prognostic factors.
出处 《内蒙古中医药》 2008年第9期4-6,共3页 Inner Mongolia Journal of Traditional Chinese Medicine
关键词 鳞状细胞 唇肿瘤 病理学 口腔 Carcinoma Squamous cell Lip tumor Pathology Oral
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