期刊文献+

儿童肥胖临床相关病理机制研究进展 被引量:4

下载PDF
导出
摘要 儿童肥胖是由遗传、代谢、内分泌失调、不良生活习惯等多种因素引起的综合征.99%的儿童肥胖是单纯性肥胖。遗传及环境因素是儿童肥胖发生的重要因素。儿童肥胖与代谢综合征、心血管损害、胰岛素抵抗及肝脏脂肪变性关系密切。现就儿童肥胖临床相关病理机制的进展综述如下:
出处 《中日友好医院学报》 2008年第5期300-302,共3页 Journal of China-Japan Friendship Hospital
  • 相关文献

参考文献27

  • 1Viner RM,Segal TY,Lichtarowicz-Krynska E,et al.Prevalence of the insulin resistance syndrome in obesity[J].Arch Dis Child, 2005,90( 1 ):10-14.
  • 2Botton J,Heude B,Kettaneh A,et al.Cardiovascular risk factor levels and their relationships with overweight and fat distribution in children:the Fleurbaix Laventie Ville Sante Ⅱ study[J]. Metabolism, 2007,56 ( 5 ) :614-622.
  • 3de-Silva KS,Wickramasinghe VP,Gooneratne IN.Metabolic consequences of childhood obesity-a preliminary report[J]. Ceylon Med J,2006,51(3):105-109.
  • 4Kaufman CL,Kaiser DR,Steinberger J,et al.Relationships of cardiac autonomic function with metabolic abnormalities in childhood obesity [J].Obesity-(Silver-Spring),2007,15 (5): 1164-1171.
  • 5Singhal A.Endothelial dysfunction:role in obesity-related disorders and the early origins of CVD [J].Proc Nutr Soc, 2005,64( 1 ):15-22.
  • 6Huang RC,Burke V ,Newnham JP,et al.Perinatal and childhood origins of cardiovascular disease[J].Int J Obes-(Lond), 2007,31 (2):236-244.
  • 7Meyer AA,Kundt G,Steiner M,et al.Impaired flow-mediated vasodilation,carotid artery intima-media thickening,and elevated endothelial plasma markers in obese children:the impact of cardiovascular risk factors[J].Pediatrics, 2006,117 (5): 1560-1567.
  • 8Csernus K,Lanyi E,Erhardt E,et al.Effect of childhood obesity and obesity -related cardiovascular risk factors glomerular and tubular protein excretion [J].Eur J Pediatr, 2005,164(1):44-49.
  • 9戴永利,王君霞,薛晓茹,周少宏.儿童肥胖与胰岛素敏感性的关系研究[J].中国现代医学杂志,2007,17(10):1227-1228. 被引量:8
  • 10Zou CC,Liang L,Hong F.Relationship between insulin resistance and serum levels of adiponectin and resistin with childhood obesity[J]. Indian-Pediatr,2007,44(4):275-279.

二级参考文献79

共引文献73

同被引文献22

  • 1张力,米杰,程红,赵小元,候冬青,单晓益.学龄儿童动脉顺应性的年龄性别分布及相关因素[J].中国循环杂志,2006,21(2):121-124. 被引量:4
  • 2刘青,郭蔚莹,迟宝荣.脂联素与胰岛素抵抗及2型糖尿病关系的研究进展[J].吉林大学学报(医学版),2006,32(6):1142-1145. 被引量:7
  • 3高磊,李卫华.动脉顺应性的研究进展[J].心血管病学进展,2007,28(1):74-76. 被引量:17
  • 4Zou CC,Liang L,Hong F,et al.Glucose metabolism disorder in obese children assessed by continuous glucose monitoring system [J ]. World J Pediatr,2008, 4( 1 ):26-30.
  • 5Mather K, Anderson TJ,Venna S. Insulin action in the vasculature physiology and pathophysiology [ J ]. J Vase Res,2001,38 ( 5 ):415-422.
  • 6Woo KS,Chook P, Yu CW,et al. Overweight in children is associated with arterial endothelial dysfunction and intima-media thickening [J ]. Int J Obes Relat Metab Disord,2004,28(7 ):852-857.
  • 7Otsuka F,Sugiyama S,Kojima S. Hypoadiponectinemia is associated with impaired glucose tolerance and coronary artery disease in non-diadetic men[J].{H}CIRCULATION JOURNAL,2007,(11):1703-1709.
  • 8Broedl UC,Lebherz C,Lehrke M. Low adiponectin levels are an independent predictor of mixed and non-calcified coronary atherosclerotic plaques[J].Plos One,2009,(03):4733.
  • 9Hotta K,Funahashi T,Bodkin NL. Circulating concent rations of the adipocyte protein adiponect are decreased in parallel with reduced insulin sensitivity during the progression to type 2 diabetes in rhesus monkeys[J].{H}DIABETES,2001,(05):1126-1133.
  • 10OwenKR,Thanabalasingham G,James TJ. Assessment of high-sensitivity C-creactive protein levels as diagnostic discriminator of maturity-onset diabetes of the young due to HNF1A mutations[J].{H}DIABETES CARE,2010,(09):1919-1924.

引证文献4

二级引证文献15

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部