穿透性角膜移植术治疗晚期圆锥角膜的疗效观察

The curative effect of penetrating keratoplasty for terminal keratoconus

目的探讨穿透性角膜移植术治疗晚期圆锥角膜的疗效。方法穿透性角膜移植术治疗11例(14只眼)晚期圆锥角膜患者,术后随访12～48个月,比较术前、术后视力变化。结果术后所有裸眼视力与术前比较均有明显提高,有显著差异。14只眼角膜植片均透明。其中3只眼术后发生排斥反应,经治疗后恢复透明。1只眼虹膜前粘连。结论穿透性角膜移植术治疗晚期圆锥角膜可显著提高视力,且并发症少,目前是一种安全有效的治疗方法。

Objective To evaluate the curative effect of penetrating keratoplasty （ PKP ） for terminal keratoconus. Methods Eleven patients （14eyes） with terminal keratoconus underwent PKP, and than followed up for 12mons to 48mons. The change of visual acuity before and after treatment was observed. Results The uncrrected visual acuity before and operation was higher than that before operation. All the corneal grafts were transparent. Three eyes had rejection and became transparent after treatment, one eye had synechia iridis anterior. Conclusion PKP can improve the visual acuity in patients with tem：inal keratoconus,is a safe and effective treatment at present.