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FcRL基因家族的研究进展 被引量:1

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摘要 越来越多的细胞表面受体被确认具有能通过T细胞受体或B细胞受体调节免疫应答的能力。Fc受体样(Fc receptor like or homolog,FcRL/H)基因是近年发现的基因,自Georgia等对骨髓瘤易位染色体(1;14)(q21;q23)断点区进行克隆发现了两个新的基因,即FcRLA(IRTA1)和FcRL5(IRTA2)后,相继有新的类似基因被发现。目前人类FcRL基因家族中至少有6个成员,其编码的蛋白质分子的胞外域具有3~9个Ig样结构域,
作者 桑道乾
出处 《中华微生物学和免疫学杂志》 CAS CSCD 北大核心 2008年第9期862-866,共5页 Chinese Journal of Microbiology and Immunology
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