期刊文献+

利血平分子印迹聚合物在饲料检测中的应用

Application of Molecularly Imprinted Polymers for Determination of Reserpine in Feed
下载PDF
导出
摘要 以获得的利血平(Reserpine,RES)分子印迹聚合物为填料,制备出分子印迹固相萃取小柱,对饲料中的利血平进行富集、纯化;结合高效液相色谱法,建立了基于分子印迹技术的检测饲料中利血平的新方法,灵敏度达0.05μg/g,回收率达80%以上,可应用于实际检测。 The obtained molecularly imprinted polymers (MIPs) against reserpine (RES) was used as solid phase extraction adsorbents for enrichment and purification of reserpine in feed. Combined with regular HPLC analysis, the new method for reserpine determination based on molecularly imprinted polymers technology was developed, with sensitivity of 0. 05 μg/g, and recovery rate above 80%. This new method can be applied in practice.
出处 《中国农业科技导报》 CAS CSCD 2008年第5期75-78,共4页 Journal of Agricultural Science and Technology
基金 国家863计划项目(2006AA10Z438)资助
关键词 利血平 分子印迹聚合物 固相萃取 reserpine molecularly imprinted polymers solid phase extraction
  • 相关文献

参考文献10

  • 1Sreemantula S, Boini K M, Nammi S. Reserpine methonitrate, a novel quaternary analogue of reserpine augments urinary excretion of VMA and 5-HIAA without affecting HVA in rats[ J]. BMC Pharmacology, 2004, 4: 30.
  • 2Chen F E, Huang J. Reserpine: a challenge for total synthesis of natural products [ J ]. Chem. Rev. , 2005, 105 : 4671 - 4706.
  • 3Varehi G, Battaglia A, Samor C, et al.. Synthesis of deserpidine from reserpine [ J ]. J. Nat. Prod. , 2005, 68 : 1629- 1631.
  • 4Anderson M A, Wachs T, Henion J D. Quantitative ionspray liquid chromatographic/tandem mass spectrometric determination of reserpine in equine plasma [ J ]. J. Mass Spectra, 1997, 32 : 152 - 158.
  • 5Cao W D, Yang X R, Wang E K. Determination of reserpine in urine by capillary alectrophoresis with electrochemiluminescence detection[J]. Electroanalysis, 2004, 16 : 169 - 174.
  • 6Pinotsis N, Catokerinos A C, Baeyens W R. Chemiluminomettic determination of reserpine and re]ated alkaloids [ J ]. Analyst, 2000, 125:1307-1311.
  • 7Chen H W, He Q H. Flow injection spectrofluofimetric determination of reserpine in tablets by on-line acetone sensitized photochemical reaction[J]. Talanta, 2000, 53:463 -469.
  • 8Singh D K, Srivastava B, Sahu A. Spectrophotometric determination of rauwolfia alkaloids: estimation of reserpine in pharmaceuticals[J]. Anal. Sci. , 2004, 20:571 -573.
  • 9欧阳晓玫,何英梅,常琦.RP-HPLC法测定利血平片剂的含量[J].中国药事,2003,17(12):758-759. 被引量:5
  • 10Shi X Z, Wu A B, Qu G R, et al.. Development and characterisation of molecularly imprinted polymers based on methacrylic acid for selective recognition of drugs[ J]. Biomaterials, 2007, 28 : 3741 - 3749.

二级参考文献1

  • 1.中国药典[S]:二部[M].,2000.305.

共引文献4

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部