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骨盆骨折病人血浆D-二聚体变化及其临床意义

CLINICAL SIGNIFICANCE OF CHANGES IN PLASMA LEVELS OF D-DIMER IN PATIENTS WITH PELVIC FRACTURE
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摘要 目的观察骨盆骨折病人血浆D-二聚体的变化。方法采用免疫比浊法测定32例骨盆骨折病人的血浆D-二聚体水平。结果骨盆骨折病人伤后1、7、14 d时血浆中D-二聚体浓度均比正常对照组升高(t=2.98-4.30,P〈0.01)。结论骨盆骨折病人由于伤后继发的纤溶亢进导致血浆D-二聚体水平增高,影响了该时期它作为血栓形成监测指标的可靠性。 Objective To observe the changes of plasma level of D-dimer following pelvic fracture. Methods Plasma levels of D-dimer in 32 patients were detected by immunoturbidimetry. Results The levels of D-dimer in the patients were significantly higher than those of the normal controls group on the 1st, 7th, and 14th clay after injury (t=2.98-4.30,P〈0.01). Conclusion The reliability of D-dimer assay is affected, due to its higher level after injury caused by secondary fibrinolytic augmentation, for predicting thrombogeneis in patients with pelvic fracture.
出处 《齐鲁医学杂志》 2008年第5期431-432,共2页 Medical Journal of Qilu
关键词 骨盆 骨折 D-二聚体 Pelvis Fracturesf D-dimer
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