水晶丹治疗痛风性关节炎急性发作135例临床观察

Treatment of acute gouty arthritis with shuijingdan

目的探讨水晶丹外敷治疗痛风性关节炎急性发作的有效性和安全性。方法135例痛风性关节炎急性发作的患者随机分为两组。两组给以低嘌呤低脂饮食、患肢制动、碱化尿液基础治疗。治疗组给以水晶丹外敷罹患关节,每日更换1次;对照组给以3餐后口服吲哚美辛肠溶片50mg;10d 1个疗程。结果135例患者均完成治疗。治疗组在疼痛、肿胀和功能评定明显优于对照组(P<0.05),对照组的不良反应明显多于治疗组(P<0.001)。结论水晶丹外敷能有效、安全地缓解痛风性关节炎急性发作的骨关节炎性反应,但无证据表明水晶丹能降低血尿酸。

Objective To evaluate the therapeutic efficacy and safety of applying ShuiJingDan in the treatment of acute gouty arthritis. Methods 135 Paitients acute gouty arthritis were random classified intotwogroups. Give the two groups the same basic-treatment：low-fat and low purine diet, brake, alkalization urine. Patients in study group were treated with applying ShuiJingDan once a day, the control group with oral Indomethaci after The three meals. Ten day is the one course of treatment. Results All the 135 case received the treatment. The swelling, pain and function assessment of study group were obvious superior to those of control one （ P 〈 0.05 ） . There were more side-effects in control group（ P 〈 0.01 ）. Conclusion SuiJingDan alleviate the osteoarticular inflammatory response in acute occurrence of arthrolithiasia effectively and safely.There was no evidence on ShuiJingDan decreasing uric acid in blood.