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白细胞介素-10、白细胞介素-6在急性冠状动脉综合征中的临床意义

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摘要 目的探讨白细胞介素-6(IL-6)、白细胞介素-10(IL-10)在急性冠状动脉综合征(ACS)的血清变化。方法采用ELISA法检测45例ACS患者,20例稳定性心绞痛(SAP)患者,20例对照者血清IL-10I、L-6水平。结果ACS组血清-6水平较SAP组、对照组升高,ACS:(25.81±4.79)ng/L,SAP:(10.79±2.07)ng/L;(7.65±1.71)ng/L,均P<0.05;冠心病各组血清IL-10水平高于对照组,ACS:(18.23±3.42)ng/L,SAP:(15.20±4.98)ng/L,对照组:(9.40±3.09)ng/L,均P<0.05,ACS组与SAP组比较差异无统计学意义(P>0.05);而ACS组血清IL-6/IL-10比值高于SAP组及对照组,ACS:(1.69±0.53),SAP:(1.06±0.38),对照组:(0.92±0.41),均P<0.05。结论ACS患者血清IL-6及血清IL-6/IL-10比值升高,ACS患者存在炎症因子及抗炎因子分泌失衡。
作者 邓学军 覃数
出处 《四川医学》 CAS 2008年第10期1355-1356,共2页 Sichuan Medical Journal
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