沙眼衣原体、解脲支原体感染引起输卵管性不孕的临床分析

CLINICAL ANALYSIS OF TUBAL INFERTILITY CAUSED BY INFECTION OF CHLAMYDIA TRACHOMATIS AND UREAPLASMA UREALYTICUM

[目的]探讨生殖道沙眼衣原体(CT)、解脲支原体(UU)感染对输卵管性不孕的影响。[方法]选取输卵管完全阻塞的不孕症患者66例、输卵管部分阻塞的不孕症患者116例、输卵管通畅的不孕症患者90例。应用聚合酶链反应(PCR)技术对其宫颈分泌物进行CT、UUDNA片段的扩增检测。[结果]输卵管完全阻塞组、输卵管部分阻塞组的不孕症患者的CT、UU及2者合并感染率显著高于输卵管通畅组的不孕症患者,比较差异有统计学意义(P﹤0.05);输卵管完全阻塞组和输卵管部分阻塞组之间的比较差异无统计学意义(P﹥0.05)。[结论]CT、UU感染可引起宫颈炎、子宫内膜炎、输卵管炎及积水等炎症,是造成输卵管性不孕的主要原因之一,与输卵管性不孕有密切的关系。

[Objective] To study the effect of tubal infertility on the chlamydia trachomatis （CT） and ureaplasma urealyticum （UU）. [ Methods] 66 cases of infertile patients diagnosed as tubal completely obstruction group and 116 cases diagnosed as tubal incompletely obstruction group were investigated. 90 cases of infertile patients with normal tube were selected as control group. CT and UU DNA in their cervical excretion were detected by method of polymerase chain reaction （PCR）. [ Resuits] The infection rates of CT, UU and CT plus UU in incompletely obstruction group were significantly higher than those in control group （P 〈 0.05）, and the rats in tubal completely obstruction group did not found significandy difference with the tubal incompletely obstruction group （P 〉 0.05）. [ Conclusion] The infection of CT and UU might cause infection of cervicitis, endometritis, salpingitis, hydrops and so on. which is the main reason to cause the tubal infertility and has close association with tubal infertility.