早期干预促进早产儿智能发育的病例-对照研究

Case-control study of early intervention on the intellectual development of preterm infants

【目的】探讨早期干预对早产儿智能发育的影响,以改善其预后。【方法】采用病例-对照研究方法,将在罗湖区妇幼保健院住院分娩或就诊的早产儿236例,分为早期干预组106例和对照组130例,两组资料在性别构成、胎龄、出生体重、新生儿窒息、缺氧缺血性脑病和颅内出血的发生情况差异无显著性（P〉0.05）。干预组按0-2岁早期干预大纲进行干预训练。由专人定期行体格发育与神经系统检查及智力测定。对照组只接受常规育儿指导。【结果】观察组在智能发育各纬度得分及发育商均显著高于对照组（P〈0.01）;体格发育情况组间差异无显著性（P〉0.05）。【结论】早期干预可促进早产儿智能发育,值得推广。

【Objective】 To explore the influence of early intervention on the intellectual development of premature. 【Methods】 Case-control study was used,and 236 premature children delivered or visited in our hospital were divided into early intervention group（n=106） and control group（n=130）.No significant difference existed between the intervention group and the control group regarding the Apgar score,degree of asphyxia of newborn,hypoxic-ischemic encephalopathy and intracranial hemorrhage（P〉0.05）.Intervention was performed on preterm infants in the early intervention group according to the early intervention programming on 0～2 years old,and special messengers checked their physical constitution,nervous system and intelligence,and the control group received common instruction only. 【Results】 The intelligence score of the intervention group was higher than that of the control group with a significant statistical significance（P〈0.01）.No significant difference existed between the groups on physical constitution（P〉0.05）. 【Conclusion】 The intellectual development of preterm infants can be enhanced by the practice of early intervention,which is worth generalization.