摘要
目的评价甘油止痒液对烧伤患者的止痒效果。方法160例康复期烧伤患者应用甘油止痒液,分析其止痒效果、起效时间、缓解时间及不良反应。结果完全缓解(CR)率为30.8%,部分缓解(PR)率为60.0%,总有效率为90.8%。平均起效时间为(4.09±0.39)min,最佳缓解时间为(12.70±0.27)min,缓解时间为(14.3±1.3)h。连续用药10次以上的患者与连续用药10次以下者相比CR、PR以及缓解时间差异无统计学意义。副作用为用药时轻微的刺痛及用药后轻微的皮肤烧灼感,但均可耐受。结论甘油止痒液对烧伤患者的止痒效果确切,安全性大,持续时间长,可作为烧伤患者较理想的外用止痒药物。
Objective To evaluate the effect of glycerine itching-relieving solution to scald and burn patients. Methods Investigating the itching-relieving effect of glycerol itching-relieving solution to scald and bum patients. Analyzing the itching-relieving effect, the onset of action, the lasting time and side effects of glycerol itching-relieving solution to severe and moderate itching scald and bum patients. Results The complete relief rate （CR） is 30.8%, while the part relief rate （PR） is 60.0%. So the total relief rate is 90.8%. The mean onset time of activation is （4.09±0.39） min, and the optimal itching-relieving time is （ 12.70± 0.27） min and the mean lasting time is （ 14.3 ± 1.3 ） h. The CR in patients with more than 10 times of continuous treatment is as long as which in ones with less than 10 times. So do the PR and the lasting time. The side effects of this drug are as follows, mild stabbing pain and the slight feeling of burning sensation of skin, but all of these can be tolerable. Conclusion Glycerine itching-relieving solution is an effective and safe agent to serve as itching-relieving treatment, and it can be regarded as an ideal one to relieve itch.
