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中国陕西汉族骨髓供者HLA—A位点基因多态性的PCR—SBT分型初步研究

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摘要 目前对于中国北方人群HLA—A座位基因多态性研究多采用中低分辨率的PCR—SSP和PCR—SSO技术,缺乏来自较大样本量精确的高分辨基因分型数据。我们应用聚合酶链反应-碱基序列直接测序分型(PCR—SBT)技术,对中华骨髓库陕西分库中随机抽取的166名陕西汉族骨髓供者HLA—A座位基因进行了DNA测序,分析该组等位基凶多态性、基因频率及优势基因构成特征。现报告如下。
机构地区 陕西省血液中心
出处 《中华血液学杂志》 CAS CSCD 北大核心 2008年第10期701-703,共3页 Chinese Journal of Hematology
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参考文献11

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二级参考文献32

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