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瞬时感受器电位超家族与血管平滑肌功能 被引量:3

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摘要 血管平滑肌的功能主要是通过多种机制激活Ca^2+内流使胞内Ca^2+浓度持续升高来实现的。目前的研究表明这种Ca^2^+内流与一系列瞬时感受器电位超家族成员有关,瞬时感受器电位超家族主要成员有:瞬时感受器电位C1、C3~6、V1、V2、V4、M4、M7和P2。文章概述瞬时感受器电位在血管平滑肌功能方面的作用。
出处 《中国动脉硬化杂志》 CAS CSCD 2008年第8期659-661,672,共4页 Chinese Journal of Arteriosclerosis
基金 国家自然科学基金资助项目(30670772) 福建省自然科学基金资助项目(C0620002)
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  • 1Parekh AB, Putney JW Jr. Store-operated calcium channels [J]. Physiol Rev, 2005, 85 (2): 757-810.
  • 2Pedersen SF, Owsianik G, Nilius B. TRP channels: an overview [J]. Cell Calcum, 2005, 38 (3-4): 233-252.
  • 3段波,徐天乐.TRP通道与信号转导[J].生物物理学报,2005,21(4):245-260. 被引量:18
  • 4Ryuji I,Lars JJ,Juan S,et al.Transient receptor potential channels in cardiovascular function and disease[J].Circ Res, 2006, 99 (2): 119-131.
  • 5Lin MJ, Leung GP, Zhang WM, et al. Chronic hypoxia-induced upregulation of store-operated and receptor-operated Ca^2+ channels in pulmonary arterial smooth muscle ceils: a novel mechanism of hypoxic pulmonary hypertension [J]. Circ Res, 2004, 95 (5): 496-505.
  • 6Mandegar M, RemlUard CV, Yuan JX. Ion channels in pulmonary arterial hypertension [J]. Prog Cardiovasc Dis, 2002, 45 (2): 81-114.
  • 7Moneer Z, Pino I, Emily JA, et al. Different phospholipase C-coupled receptors differentially regulate capacitative and non-capacitatlve Ca^2 + entry in A7r5 cells [J]. Biochem J, 2005, 389 (3) : 821- 829.
  • 8Worley PF, Zeng WZ, Huang GN, et al. TRPC channels as STIM1-regulated store-operated channels [J]. Cell Calcium, 2007, 42 (2): 205-211.
  • 9Yang XR,Lin MJ,McIntosh LS,et al.Functional expression of transient receptor potential melastatin-and vanilloid-related channels in pulmonary arterial and aortic smooth muscle[J].Am J Physiol Lung Cell Mol Physiol.2006, 290 (6) : 1 267-276.
  • 10Beech DJ, Xu SZ, McHugh D, et al. TRPCI : store-operated cationic channel subunit [J]. Cell Calcum 2003, 33 (5-6) : 433- 440.

二级参考文献86

  • 1Zhu X, Jiang M, Peyton M, Boulay G, Hurst R, Stefani E,Birnbaumer L. trp, a novel mammalian gene family essential for agonist-activated capacitative Ca^2+ entry. Cell, 1996,85:661-671.
  • 2Moqrich A, Hwang SW, Earley TJ, Petrus MJ, Murray AN,Spencer KS, Andahazy M, Story GM, Patapoutian A .Impaired thermosensation in mice lacking TRPV3, a heat and camphor sensor in the skin. Science, 2005,307:1468-1472.
  • 3Guler AD, Lee H, Iida T, Shimizu I, Tominaga M, Caterina M. Heat-evoked activation of the ion channel, TRPV4.J Neurosci, 2002,22:6408-6414.
  • 4Viana F, de la Pena E, Belmonte C. Specificity of cold thermotransduction is determined by differential ionic channel expression. Nat Neurosci, 2002,5:254-260.
  • 5Viswanath V, Story GM, Peier AM, Petrus MJ, Lee VM,Hwang SW, Patapoutian A, Jegla T. Opposite thermosensor in fruitfly and mouse. Nature, 2003,423:822-823.
  • 6Caterina MJ, Leffler A, Malmberg AB, Martin WJ, Trafton J,Petersen-Zeitz KR, Koltzenburg M, Basbaum AI, Julius D.Impaired nociception and pain sensation in mice lacking the capsaicin receptor. Science, 2000,288:306-313.
  • 7Ross RA. Anandamide and vanilloid TRPV1 receptors. Br J Pharmacol, 2003,140:790-801.
  • 8Corey DP, Garcia-Anoveros J, Holt JR, Kwan KY, Lin SY,Vollrath MA, Amalfitano A, Cheung EL, Derfler BH, Duggan A, Geleoc GS, Gray PA, Hoffrnan NIP, Rehm HL,Tamasauskas D, Zhang DS. TRPA1 is a candidate for the mechanosensitive transduction channel of vertebrate hair cells.Nature, 2004,432:723-730.
  • 9Nagata K, Duggan A, Kumar G, Garcia-Anoveros J. Nociceptor and hair cell transducer properties of TRPA1, a channel for pain and hearing. J Neurosci, 2005,25:4052-4061.
  • 10Zhang y, Hoon MA, Chandrashekar J, Mueller KL, Cook B,Wu D, Zuker CS, Ryba NJ. Coding of sweet, bitter, and umami tastes: different receptor cells sharing similar signaling pathways. Cell, 2003,112:293-301.

共引文献23

同被引文献28

  • 1Lin MJ, Leung GP, Zhang WM, et al. Chronic hypoxia-induced upregulation of store-operated and receptor-operated Ca^2+ channels in pulmonary arterial smooth muscle cells: a novel mechanism of hypoxic pulmonary hypertension[J].Circ Res, 2004, 95 (5) : 496 - 505.
  • 2Várnai P,Hunyady L,Balla T.STIM and Orai:the long-awaited constituents of store-operated calcium entry[J].Trends Pharmacol Sci,2009,30(3):118-128.
  • 3Brandman O,Liou J,Park WS,et al.STIM2 is a feedbackregulator that stabilizes basal cytosolic and endoplasmic re-ticulum Ca2+levels[J].Cell,2007,131(7):1 327-339.
  • 4Deng X,Wang Y,Zhou Y,et al.STIM and Orai:dynam-ic intermembrane coupling to control cellular calcium sig-nals[J].J Biol Chem,2009,284(34):22 501-505.
  • 5Hogan PG,Lewis RS,Rao A.Molecular basis of calciumsignaling in lymphocytes:STIM and ORAI[J].Annu RevImmunol,2010,28:491-533.
  • 6Smyth JT,Hwang SY,Tomita T,et al.Activation and reg-ulation of store-operated calcium entry[J].J Cell MolMed,2010,14(10):2 337-349.
  • 7Stathopulos PB,Zheng L,Li GY,et al.Structural andmechanistic insights into STIM1-mediated initiation of store-operated calcium entry[J].Cell,2008,135(1):110-122.
  • 8Oh-Hora M,Yamashita M,Hogan PG,et al.Dual func-tions for the endoplasmic reticulum calcium sensors STIM1and STIM2 in T cell activation and tolerance[J].Nat Im-munol,2008,9(4):432-443.
  • 9Ji W,Xu P,Li Z,et al.Functional stoichiometry of the u-nitary calcium-release-activated calcium channel[J].ProcNatl Acad Sci USA,2008,105(36):13 668-673.
  • 10Muik M,Frischauf I,Derler I,et al.Dynamic coupling ofthe putative coiled-coil domain of ORAI1 with STIM1 medi-ates ORAI1 channel activation[J].J Biol Chem,2008,283(12):8 014-022.

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