欧亚旋覆花黄酮类化学成分研究

Identification of Flavonoids in Inula britannica

目的:研究欧亚旋覆花的黄酮类化学成分。方法:用95%乙醇提取欧亚旋覆花,并用各种柱色谱分离纯化,通过测定理化常数和光谱分析鉴定其结构。结果:分离得到10个黄酮类化合物,经鉴定为菠叶素(1)、6-甲氧基-木犀草素(2)、木犀草素(3)、槲皮素(4)、异鼠李素(5)、山柰酚(6)、芦丁(7)、万寿菊苷(8)、异槲皮苷(9)和槲皮苷(10)。其中,化合物5、7、10为首次从欧亚旋覆花植物中得到。结论:本试验可为欧亚旋覆花的进一步研究提供科学依据。

OBJECTIVE： To study the flavonoids in Inula britannica .METHODS： The Inula britannica was extracted with 95% ethanol and isolated and purified by different column chromatography, the structures of the constituents were derived by measuring the physicochemical constants and spectral analysis. RESULTS：A total of 10 flavonoids were isolated from Inula britannica which were stated as follows：Spinacetin（1） ,6- methoxy - luteolin（2）, Iuteolin（3） ,Quercetin（4）, Isorhamnetin（5）, Kaempferol（6）, Rutin（7）, Patulitrin（8）, Isoquercitrin（9） and Quercitrin（10） .Of which, compounds 5, 7 and 10 were isolated from Inula britannica for the first time. CONCLUSION： This result serves as a scientific basis for the further study of Inula britannica .