自身血液预处理透析器对预防首次使用综合征的临床价值

Study on the self-blood pretreatment to the dialyzer obviating First-use related syndrom

目的探讨自身血液预处理透析器对减少血液透析病人出现透析器首次使用综合征(FUS)的临床价值。方法将78例透析病人随机分为治疗组与对照组,每组各39例。对照组在新透析器使用前用0.8%过氧乙酸对透析器重新灭菌消毒,密闭保存24小时以上再次使用;治疗组在最后一次使用复用型透析器时,在回血时用生理盐水500ml回血,用透析管路内残存洗肉水样血水约20ml给予新透析器,加生理盐水150ml密闭循环20分钟,然后再放掉血水,用0.8%过氧乙酸消毒,密闭保存24小时以上再使用。结果治疗组FUS发生率5.1%,对照组12.8%,两组比较,差异有显著性意义(P<0.01)。结论用自身血液预处理透析器可明显降低FUS的发生。

Objective To discuss effect of the self-blood pretreatment of the dialyzer on the first-use related syndrom（FOS） in hemodialysis patients. Methods 78 patients were divided into two groups, including control group （39 cases） and treatment group （39 cases）. The dialyzer used in control group was cleared with 0. 8% peracetic acid, which was maintained at least 24h. The dialyzer used in treatment was cycled was 0.9%NS 500ml and the remained blood, maintained with 0. 80% peracetic acid at least 24h. Results In treatment group, the incidence of FUS was 5.1%, significant lower than that in control group （P〈0. 01）. Conclusion The treatment of blood-water in dialysis tube could decrease the incidence of FUS.