甲钴胺对2型糖尿病周围神经病变的治疗作用

Effects of mecobalamin on the diabetic peripheral neuropathy

目的观察甲钴胺对2型糖尿病周围神经病变(DPN)的疗效。方法将120例DPN患者随机分为两组,在基础治疗相同的情况下,治疗组60例加用甲钴胺注射液治疗,对照组60例未使用该药。两组病人均连续用药1个月。观察甲钴胺对DPN患者临床疗效和肌电图的影响。结果治疗组总有效率为81.67%,对照为53.33%,两组比较有显著性差异(P<0.01)。在改善患者肌电图方面,治疗组优于对照组。结论甲钴胺治疗DPN有较好的疗效。

Objective The present study investigated the therapeutic effects of mecobalamin on diabetic neuropathy with type 2 diabetes. Methods 120 cases were randomized divided into two groups, including Group treatment （60 patients） and Group control （60 patients）. Group treatment was treated with mecobalamin, whereas Group control was not. The two groups were under the same basic therapy and treated for 1 month. The effects of mecobalamin were observed. Results The total effective rate of Group treatment and Group control were 81.67% and 53.33%, respectively （P〈0.01）. Group treatment on improving the electromyogram was prior to Group control （P〈 0. 05）. Conclusion Mecobalamin is effective for DPN.