氟康唑治疗慢性阻塞性肺疾病并发白色念珠菌感染64例疗效观察

Clinical Observation of the Fluconazole in Chronic Pulmonary Disease with Monliasis Infection

目的:观察氟康唑治疗慢性阻塞性肺疾病(COPD)并发白念珠菌感染的疗效及不良反应。方法:用氟康唑治疗COPD并发白色念珠菌感染64例,首剂400mg静脉点滴,后1次/d200mg静脉点滴,7d^14d,改为1次/d100mg口服,总疗程2周~4周;口咽部感染配合用1∶5氟康唑溶液,每日涂擦口咽部3次,连用5d^7d。结果:总有效率为90.6%,不良反应发生率为10.9%。结论:氟康唑治疗白色念珠菌感染疗效高,用药方便,不良反应少,适用于COPD患者。

Objective To observe the treating effect and side effect of fluconazole in COPD patients with monliasis infection. Methods Fluconazole Injections were administered in adaily dose of 200 rag/7-14 days in 64 COPD patients with monliasis,then fluconazole capsules were givens in a dose of 100 mg everydays. The total treating time was 2-4 weeks. The period of daubing the mouth and throat three times everyday with 1：5 fluconazole solution was 5-7 days when the mouth and throat were infected. Results The total effective rate was 90.6%. The incidence rate of side effects was 10.9%. Conclusion Fluconasole is fit for COPD patients with monliasis infection,it has higher curing rate, convenient administration and less side effects.