丙泊酚自控镇静在全小肠镜检查中的应用

Patient-controlled sedation with propofol in small intestinal endoscopy

目的观察丙泊酚患者自控镇静在全小肠镜检查中的效果。方法32例全小肠镜检查的患者，随机分为2组：对照组14例和丙泊酚组18例。对照组行常规全小肠镜检查，不使用任何麻醉性镇痛、镇静药；丙泊酚组通过奥美PCA注射泵由患者自行控制使用丙泊酚进行自控镇静。两组检查过程中持续检测ECG、心率、血压、SPO2，并行患者镇静程度评分，检查完毕后询问检查过程中的感受和满意度。结果检查过程中对照组和丙泊酚组相比：心率、血压显著升高，SPO2显著下降（P〈0．05）；丙泊酚组镇静评分和满意程度显著优于对照组（P〈0．05），对照组全部患者因检查过程中不能耐受而改为丙泊酚静脉麻醉。结论丙泊酚患者自控镇静用于全小肠镜检查具有安全、循环稳定等优点，能增强患者的配合程度和舒适度。

Objective To study the effect of patient- controlled sedation（PCS） with propofol during small intestinal endoscopy. Methods Thirty-two patients undergoing small intestinal endoscopy were randomly divided into two groups：group C（control group, n = 14） and group P （propofol group, n = 18）. Patient- controlled sedation was performed with 1.5 mg/kg loading dose without continuing dose.0.5 mg/kg bolusdose of propofol was self- administered without intervals in group P. Sedation level was evaluated, ECG, BP, HR, and SPO2 were monitored in all patients. Results There was no significant change of the hemodynamics in the two groups（ P 〉 0.05）. BP, HR and RPP were higher in group C than that in group P（ P 〈 0.05） .The level of sedation in group P higher than that in control group. Conclusions Patient - controlled sedation with propofol in small intestinal endoseoov is safe and decreases the level of stress response.