小剂量米力农和多巴酚丁胺治疗扩张型心肌病疗效比较

A Comparison of Clinical Effects of Lowdose Milrinone and Dobutamine in Treating Dilated Cardiomyopathy

报告小剂量国产米力农静脉滴注治疗扩张型心肌病（ＤＣＭ）充血性心力衰竭（ＣＨＦ）患者３２例，并与多巴酚丁胺治疗组３０例进行疗效比较。结果表明，米力农治疗的患者总有效率达９０．６％，明显高于多巴酚丁胺治疗组６６．７％（Ｐ＜０．０５）。米力农治疗组心胸比率回缩值、ＬＶＥＦ、Ｅ／Ａ显著高于多巴酚丁胺治疗组（Ｐ＜０．０１），而心率、血压两组比较无明显差异（Ｐ＞０．０５）。提示小剂量米力农是治疗ＤＣＭ所致ＣＨＦ的安全有效治疗药物。

A study was done in 62 patients with congestive heart failure (CHF) of dilated cardiomyopathy (DCM) to appraise objectively whether the effect of low dose milrinone or that of dobutamine (Dob) was better.The results showed that milrinonegroup had higher effective rate than Dobgroup (P<005),and had higher shortening value of cardiothorax ratio,LVEF and E/A than Dobgroup (P<001),but there was no significant difference in heart rate,blood pressure between the two groups(P>005).It shwed that low dose milrinone was safe and effective in treating patients with CHF of DCM.