复方氧氟沙星滴鼻液的制备及应用

Preparation and clinical applieation of compound ofloxacin nasal drop

本文拟定了复方氧氟沙星滴鼻液处方制备工艺和质量控制标准，并对其进行了稳定性试验。采用紫外分光光度法测定了氧氟沙里的吸收度，盐酸麻黄碱在波长293nm处无干扰。结果表明该制剂应用安全．疗效可靠．室温放置12mo质量仍符合要求。

We studied the method of preparation and quality control of compound ofloxacin nasal drop. The determination of ofloxacin and ephedrine hydrochloride in nasal drops was established by ultraviolet spectropho - tometry at the wavelength 293nm and by acid - alkalic titration,The stability of compound ofloxacin nasal drops were tested. The therapetic results showed the reliable curative effect and safety.