依达拉奉治疗急性脑梗死临床疗效观察

The Treatment Effect of Edaravone on Acute Cerebral Infarction

目的:观察依达拉奉在脑梗死急性期脑保护治疗中的疗效。方法:90例急性脑梗死患者,随机分为治疗组和对照组,两组常规应用防止钙离子超载治疗、抗凝治疗、抗血小板聚集治疗、活血化瘀及神经营养因子等治疗,治疗组在常规治疗的基础上加用依达拉奉注射液30mg,每日两次,2周后进行疗效评定。结果:治疗组有效率为91.3%对照组有效率为59.1%,两组间有显著差异(P<0.01)。结论:依达拉奉清除自由基功能对神经细胞有保护作用,对治疗急性脑梗死有很好的临床疗效。

Objective： To investigate clinical therapeutic Effect of edaravone in the protection of acute cerebral infarction.Method： The total of 90 patients with acute cerebral infarction were randomly allocated to therapy group and control group.Both groups had been received a routine therapy of calcium overload preventi aggregation,activating blood circulation to dissipate blood stasis and supplying neurotrophic factors,and an additional therapy of intravenous 30mg Edaravone injection twice a day for 15 days was gave to patients in therapy group.Results： The free radical scavenging was significantly higher in therapy group （91.3% vs. 59.1%, P〈 0.01）,Conclusions： Edaravone can protect neurons and had good effects in treating acute cerebral infarction.