奈普生栓联合米索前列醇片在早孕人工流产术中的应用

The Effect of the Combination of Naproxen Suppository and Misoprostol Tablet in Induced Abortion of Early Pregnancy

目的:探讨奈普生栓联合米索前列醇片在早孕人工流产术中扩张宫颈及镇痛作用。方法:随机将病例分为两组,A组:肛塞奈普生栓1枚及口服米索前列醇片1片30min后行人工流产术50例。B组:宫颈采用直径为8mm的棉签浸湿2%丁卡因放置于进宫颈内口处5min后行人工流产术50例。结果:A组用药后宫颈扩张效果良好,与B组比较有显著性差异(P<0.01)。结论:奈普生栓联合米索前列醇片在早孕人工流产术中有较好的扩张宫颈及镇痛作用,且人工流产综合征发生率较低。

Objective： To study the effect of analgesia and dilating cervix in using the combination of Naproxen Suppository and Misoprostol Tablet in induced abortion of early pregnancy. Method： 100 cases of early pregnancy patients who will suffer induced abomon were selected and they were divided to two groups in random. One Naproxen Suppository was squeezed in every patient＇s anus and one Misoprostol Tablets was took orally 30 minutes before induced abortion in group A which included 50 cases. Group B also included 50 cases. In this group one 8ram diameter cotton bud soaked in 2% Tetracaine was put beside the cervix endostoma 5 minutes before induced abortion. Results： The effect of dilating cervix in group A was better than that in group B. There was significant difference between the two groups.（P〈0.01）Conclusions： It had good effect of dilating cervix and analgesia to use the combination of Naproxen Suppository and Misoprostol Tablet in induced abortion of early pregnancy, and the incidence rate of induced abortion syndrome was lower.