前列栓质量标准的研究

Studies on The Quanlity Standard of Suppository for Prostatitis

目的建立中药复方制剂前列栓的质量标准。方法采用薄层法(TLC)对制剂中的黄芩,黄柏,血蝎进行定性鉴别,用高效液相色谱法(HPLC)对制剂中的黄芩苷进行定量分析。结果在TLC色谱中能检出黄芩,黄柏,血蝎;含量限度含黄芩苷不少于18mg/粒。结论建立的方法可对本制剂进行准确、快速的定性定量分析。

Aim To establish a quanlity control standard of Suppository for Prostatitis. Methods The technique of TLC was used to identify Radix et Rhizoma Rhei, Radix Scutellariae , Cortex Phellodendri and Sanguis Draxonis, HPLC was applied to determine the content of baicalin. Results The Radix Scutellariae , Cortex Phellodendri , Radix et Rhizoma Rhei and sanguis Draxonis can be determined by TLC. The contents of baicalin weren＇t lower than 18mg per granule. Conclusion This method is simple , sensitive , accurate and with good reproducibility. It can be used as a quanlity control standard of the drug.