怀化地区泌尿生殖道感染者支原体感染情况及耐药性分析

Analysis on Infection and Antibiotic Susceptibility Test of 330 Strains of Mycoplasma in Huaihua

目的了解泌尿生殖道感染患者解脲支原体(Uu)和人型支原体(Mh)感染及耐药情况。方法采用深圳银科支原体检测试剂盒,培养Uu和Mh,并作药物敏感试验。结果支原体的总检出率为41.98%,其女性支原体检出率(50.34%)显著高于男性(31.09%)(P<0.01),单纯Uu阳性率(30.15%)明显高于Uu+Mh混合(11.32%)和单纯Mh阳性率(0.51%)(P<0.01)。支原体对环丙沙星、氧氟沙星、司帕沙星、罗红霉素、螺旋霉素和左旋氧氟沙星耐药率均>60.00%,而强力霉素、美满霉素和交沙霉素对支原体抗菌活性好,敏感率均>80.00%。结论本地区支原体感染率高,分离出支原体具有多重耐药性和高耐药性,临床治疗需根据药敏结果选择合适的抗菌药物。

Objective To investigate the infection condition and antibiotic susceptibility test of Ureaplasma urealyticum （UU） and Mycoplasma hominis （MH）. Methods UU and MH were cultured by using the reagent kit of Yin- Ke Mycopias, ma from Shenzhen and antibiotic susceptibility tests were done. Results The total detection rate was 41.98% and the detection rate of the females （50.34 % ） was significantly higher than that of the males （31.09 % ） （P〈 0. 01 ）. only - Uu - positive （30.15 % ） was significantly higher than both UU- MH positive （11.32%） and only- MH positive （0. 51% ） （P〈 0.01）. The resistant rates to ciprofloxacin, kfloxacin, sparfloxacin, roxithromycin, spiramycin and levofloxacin were all 〉 60.00 %. The sensitive rates to doxycycline, minocycline, and josamycin were all 〉 80.00 %. Conclusions The infection rate of Mycoplasma in local area is high. Antimicrobial agents should be chosen according to antimicrobial susceptibility test results because of their high and multi - drug resistance.