全视网膜光凝联合葛芪复明Ⅲ号治疗糖尿病性视网膜病变的临床观察

A clinical study on panretinopathy photocoagulation combined with Chinese medicines in the treatment of diabetic retinopathy

目的通过比较全视网膜光凝联合葛芪复明Ⅲ号和单纯全视网膜光凝治疗糖尿病性视网膜病变的临床疗效，弥补单纯激光治疗的不足，寻找治疗糖尿病性视网膜病变的有效方法。方法临床采集2型糖尿病并发Ⅲ、Ⅳ期眼底改变的糖尿病性视网膜病变患者35例67只眼，随机分为观察组18例（34只眼），观察组行全视网膜光凝联合葛芪复明Ⅲ号治疗；对照组17例（33只眼），对照组单纯行全视网膜光凝；两组均由同一高年资医师行全视网膜光凝术。观察3个月，治疗前后对所有患者进行视力，视觉电生理，眼底荧光血管造影检查。结果治疗后，观察组总有效率为79．41％，对照组总有效率为60．61％。两组均有较好疗效，但治疗后观察组与对照组总有效率比较差异有统计学意义（P〈0.05），观察组明显优于对照组。结论全视网膜光凝联合葛芪复明Ⅲ号组治疗效果明显优于单纯全视网膜光凝组。

Objective To observe the therapeutic efficacy of the two methods to treat the diabetic retinopathy（ DR ）between the panretinopathy photocoagulation（ PRP ）combined with the medicine and the PRP only, make up the shortage of the effect of PRP, look for the valid treatment for the DR.Methods Clinically collected the 35 patients （67eyes）diagnosed as 2 diabetes concurrent with Ⅲ-IV DR, patients are divided into observed group （ 34eyes ）and contrasted group （ 33eyes ）at random, the observed group the PRP combined with the medicine,the contrasted group treated by the PRP only;All patients are treated by the same doctor.These eyes are checked respectively by the vision,F-ERG,mf-ERG,FFA before and after treating 3 month later. Results The total effectiveness of the observed group was 79.41%, the total effectiveness of the contrasted group was 60.61% ,there were significant diffience between the two groups （P 〈0.05）;Conclusion The panretinopathy photocoagulation uniting with traditional Chinese medicine （decoction GeQIFUMINGⅢ ）has more superior curative effect than panretinopathy photocoagulation only on treating the diabetic retinopathy.