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复方珍珠滴眼凝胶中冰片的含量测定方法研究 被引量:7

Study on Determination Method for Borneol in Compound Zhenzhu Ophthalmic Gel
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摘要 建立复方眼用凝胶剂中冰片的含量测定方法。以十六烷为内标物,采用毛细管柱气相色谱法测定眼用凝胶制剂中冰片的含量。龙脑在0.04~0.12μg范围内线性关系良好(r=0.9990),平均加样回收率为96.90%,RSD为1.10%。该复方眼用凝胶剂中冰片的含量测定的方法简单、快速、准确、可行。 Determination method was studied for borneol in compound ophthalmic gel. Applying hexadecane as internal standard substance, capillary gas chromatography was used to determine borneol in ophthalmic gel. A good linearity was obtained, when the concentration of borneol was between 0.04~0.12μg (r=0. 9990). The average recovery was 96.81% and RSD was 1.46%. This method is simple, reliable and accurate, and it can be used to determine borneol in ophthalmic gel.
出处 《中国药事》 CAS 2008年第10期884-886,共3页 Chinese Pharmaceutical Affairs
基金 吉林省科技发展计划项目(编号:200705487)
关键词 复方滴眼凝胶 气相色谱法 冰片 测定方法 compound ophthalmic gel GC borneol determination method
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  • 1.中国药典[S]一部[M].,2005年版.6.

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