新疆维吾尔自治区喀什试点内脏利什曼病的人群感染状况调查

Investigation on the infection status of visceral leishmaniasis in humen in Kashgar pilot, Xinjiang Uigur Autonomous Region, China

目的了解喀什试点内脏利什曼病的人群感染状况。方法选择喀什市内脏利什曼病发病率较高的村为试点,在入户普查的同时开展人群血清学调查和利什曼素皮内试验,运用SAS软件对调查结果进行综合分析。结果不同年龄组之间皮试阳性率差异有统计学意义(χ2=11.53,P<0.05),皮试阳性率随年龄的增加有逐渐增高的趋势。当地内脏利什曼病患者与既往隐性感染者之比为1∶9。试点地区曾感染过内脏利什曼病的免疫人群占36.15%(60/166),从未感染过内脏利什曼病的易感人群占61.45%(102/166),无临床症状的现感染人群占2.41%(4/166)。结论试点地区内脏利什曼病的流行状况仍然比较严重,无症状现感染者所占比例较高,具有潜在传染源的流行病学意义。

Objective To determine infection status of visceral leishmaniasis （VL） in residents in Kashgar pilot. Methods Villages with higher incidence of VL were selected as pilot, and serological investigation and leishmania dermal test（LDT） were carried out. SAS statistical software was used to analyze the data. Results The difference of LDT positive rate was significant among different ages groups （χ^2 = 11.53, P〈0.05）, and the positive rate of LDT was increased gradually with age increasing. The ratio of VL patients and recessive infection cases was 1 ： 9 in the areas. The immune population for VL occupied 36.15% （60/166）, the susceptible who had never infected with occupied 61. 45% （102/166）, and the infected currently without any symptoms occupied 2.41% （4/166）. Conclusion Epidemic situation of VL in pilot area is still serious. Proportion of the infected population currently without any symptoms is higher, which is the potential infection source.