合并糖尿病的冠心病患者特点分析

Investigation of Clinical Characteristics in Patients with Coronary Heart Disease and Diabetes Mellitus

目的:探讨合并糖尿病的冠心病患者的临床特点。方法:采用回顾性研究。选取经冠状动脉造影而确诊为冠心病的患者633例,合并有糖尿病110例患者纳入观察组,不合并有糖尿病的523例患者纳入对照组。收集病人的一般情况、心电图、超声心动图等资料,观察两组病人在高血压、高血脂、心力衰竭、心电图、心肌缺血症状等方面的发病情况。结果:(1)两组病人在发病年龄、性别、高血压、高血脂的发病情况无明显差异;心力衰竭的发生率观察组显著高于对照组。(2)心电图异常、无心肌缺血表现和心电图正常、有心肌缺血表现这两种情况在观察组中均较对照组多见。结论:(1)合并糖尿病的冠心病患者无症状心肌缺血与心电图正常的冠心病病人多见,如不能及时识别易延误诊治。(2)合并糖尿病的冠心病患者心功能损害较重,心力衰竭发生率高。

Objective To investigate the clinical characteristics in the patients with coronary heart disease and diabetes mellitus （DM）. Methods To select 633 patients with coronary heart disease by coronary angiography（CAG）. We divided these patients into two groups. One group was 110 cases with diabetes mellitus;The other was 523 cases without DM. We collected the common data,electroeardiograph（ECG）, echocardiogram, CAG , then observed the differences of hypertension, hyperlipidemia, heart failure,ECG , ischemia symptom and the characteristics of coronary lesions between the two groups. Results： 1. There were no differences between the two groups in age, sex, hypertension, hyperlipidemia but the incidence of heart failure were significantly higher in patients with DM than in the control. 2. The systole function and diastole function parameters measured by echocardiogram were significantly lower in patients with DM than in the control. 3. The incidence of patients with myocardial ischernia symptom and nomal ECG and those with abnormal ECG and without ischemia symptom were significantly higher than the control. Conclusion： It was very complicated in clinic of patients with coronary heart disease and diabetes mellitus. The patients with normal ECG or without myocardial ischemia symptom were significantly more than the control. 2. The incidence of heart failure might be significantly higher in patients with coronary heart disease and diabetes mellitus than in the contro