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辛伐他汀治疗糖尿病合并高脂血症的疗效及对血液流变学的影响 被引量:4

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摘要 目的探讨辛伐他汀治疗糖尿病合并高脂血症的疗效及对血液流变学的影响。方法选择80例2型糖尿病合并高脂血症患者,给予辛伐他汀片20 mg,每晚顿服。测定治疗前和治疗4、8周后患者血脂及血液流变学指标变化。结果治疗4、8周后患者总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白胆固醇(LDL-C)水平均较治疗前明显降低,全血高切黏度、全血低切黏度、红细胞聚集指数和红细胞压积均明显降低。结论辛伐他汀能降低2型糖尿病合并高脂血症患者血脂的水平,并可改善血液流变学指标,不良反应轻。因此,可考虑将辛伐他汀作为此类患者的调脂首选药物。
出处 《临床医学》 CAS 2008年第10期66-67,共2页 Clinical Medicine
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