中国树下丘脑视上核和室旁核内加压素能神经元的形态和神经纤维的分布

MORPHOLOGY OF THE VP-ERGIC NEURONS AND DISTRIBUTION OF THE NERVE FIBERS IN THE SON AND THE PVN OF THE HYPOTHALAMUS IN TUPAIA BELANGERI CHINENSIS

用抗加压素（VP）血清和免疫组化技术，观察了中国树下丘脑视上核（SON）和室旁核（PVN）内VP能种经元的形态和神经纤维的分布。VP能胞体的形态，在SON主部多呈梭形，少数呈多角形；在SON交叉后部，多是多角形，少数是梭形；在PVN，以多角形为主，少数为梭形．VP能纤维的分布：在PVN与SON生部之间，特别是与视交叉上区和现柬背内侧区之间，纤维细而直，多平行分布．在PVN后半外侧，可见部分纤维呈内侧-背外侧向分布；在SON交叉后部的背外侧，纤维是朝向正中隆起处汇集的趋势，其中部分纤维呈串珠状；在正中隆起内带，纤维呈西外侧-内侧向和吻-屠向密集分布，有少数大小不等的免疫反应阳性的聚集体；在正中隆起外带，特别在会体门脉毛细血管排周围，有致密的、成群分布的免疫反应阳性点状结构；在漏斗柄和垂体神经部，可见致密的免疫反应阳性纤维和Herring体，在神经部内的窦状毛细血管周围有致富的、大小不等的免疫反应阳性点状结构．

The present study demonstrated morphology of the vasopressin (VP)-ergic neurons and the distribution of the VP-ergic nerve fibers in the supraoptic (SON) and the paraventricular nuclei (PVN) of the hypothalamus of tbe Tupaia Be langeri Chinensis using VP antiserum and PAP technique. Morphology of the VP-ergic perikarya was as follow: A majority of them in the principal part of the SON (SONP) were seen to be fusiform in shape and a few of them was multipolar; In the retrochiasmatic SON (SONr) most VP-ergic perikarya were seen to be multipolar, while a few to be fusiform. In the PVN the multiPolar VP-ergic perikarya predominated over the fusiform ones. The distribution of the VP-ergic nerve fibers was as follow: They were thin and straight, parallelly distributed between the PVN and SONp, especially between the PVN and the suprachiasmatic area (SCA) and dorsomedial area of the optic tract ; A few VP-ergic nerve fibers in the second half of the PVN assumed a medial-dorsolateral orientation ; On the dorsolateral side of the SONr, the VP-ergic fibers were distributed more densely and reticularly in a dorsolateral-ventromedial orientation and showed a tendency converged to the median eminence (ME). Some of them were observed to have beaded elements ; The VP-ergic fibers were compactly distributed in a bilateral-middle and a rostral-caudal orientation and there were a few immunoreactively positive aggregates of various sizes a mong them in the internal zone of the ME: In the external zone of the ME, particularly near the portal capillary loops, there existed immunopositively stained puncta distributed in groups. In the infundibular stalk and the pars nervosa of the hypopbysis numerous dense VP-ergic fibers and a few immunopositive Herring bodies were observed. Around the sinusoid cap illaries in the pars nervosa dense immunoreactive puncta of different sizes can be frequently found. Significance of finding that the VP-ergic perikarya and the dendrite-like processes were covered with immunopositive stained spine-like or bead-likenerve elements and of VP-ergic fiber-distributing patterns were discussed.