基于聚类分析的冠心病介入术后中医证候分类及诊断

Research on TCM Syndromes and Diagnosis of Patients after Percutaneous Coronary Intervention based on Cluster Analysis

目的探讨冠心病介入术(PCI)后患者进行中医证候分类及诊断的要点。方法采用临床流行病学的方法,记录143例冠心病PCI术后患者的症状、体征(包括舌脉象)等临床资料,并对临床资料进行变量聚类分析。结果冠心病PCI术后患者出现频率较高的四诊信息依次是:胸痛、胸闷、倦怠乏力、急躁易怒、夜尿频多、形体肥胖、唇龈暗红,舌有瘀点瘀斑等;冠心病PCI术后患者证候分为6类:气虚痰浊、肾虚血瘀、肝气郁结、脾气亏虚、心气亏虚、气阴亏虚,并初步确定了各证候的诊断要点。结论冠心病PCI术后中医证候可分6型,基于四诊信息的分析可确定其各型诊断要点。

Objective To study the TCM syndromes and diagnosis of patients after percutaneous coronary intervention （PCI）. Methods The clinical epidemiological method was adopted in the study and the symptoms and signs including the manifestations of tongue and pulse of 143 patients after PCI were recorded for the variable cluster analysis. Results The most of frequently appeared symptoms and signs of patients after PCI were chest pain, chest distress, lassitude, irritability, frequent mieturition at night, obesity, dark lips andecchymosis on the tongue. The 6 involved syndromes of the patients were qi deficiency with phlegm retention, kidney deficiency with blood stasis, liver qi stagnation, qi deficiency of spleen, qi deficiency of heart, and deficiency of both qi and yin. The diagnostic points of each of them were set up. Conclusion Six syndrome type could be classified in patients after PCI, and analysis base on diagnostic information set up the diagnostic points.