慢性阻塞性肺疾病稳定期血瘀证候特点

Study on the Characteristics of Blood Stasis Syndrome of Chronic Obstructive Pulmonary Disease in the Stable Stage

目的探讨慢性阻塞性肺疾病(COPD)稳定期血瘀证候特点。方法采用自行设计的COPD中医证候信息采集表,建立证候四诊指标信息数据库。采用描述性统计分析计算中医血瘀证候四诊指标频数及分布。结果血瘀症状发生率为95.13%,血瘀证诊断病例165例,占76.74%。血瘀症状发生频数以舌下络脉粗张为多,发生率为98.1%;气虚所致血瘀症状发生率在95%以上。结论血瘀症状贯穿COPD的始终,随着病情分级的加重,血瘀证逐渐形成;舌下络脉粗张可作为COPD中医血瘀早期辨证的客观指征,爪甲紫暗的出现提示病至中晚期;因虚致瘀是COPD血瘀形成的主要病机。

Objective To study the characteristics of blood stasis syndrome of chronic obstructive pulmonary disease （COPD） at the stable stage. Methods The self-designed TCM Syndrome Information Collection of COPD was adopted and the database of Diagnostic Indices were set up. The frequency and distribution of diagnostic indices of blood stasis syndrome were calculated by the descriptive statistical analysis. Results The incidence of blood stasis symptoms was 95.13% and the 165 eases（76.74%） of blood stasis syndrome were diagnosed. The most frequently appeared symptom of blood stasis was varicose vein of the tongue（98.1%）. The incidence of blood stasis caused by qi deficiency was more than 95%. Conclusion The symptoms of blood stasis exists throughout the process of COPD and blood stasis syndrome is formed gradually with the aggravation of pathological changes. The varicosis of the tongue can be served as the early objective index in TCM syndrome differentiation. The purple dark of nails indicates that the disease has been developed into the middle or late stage. The blood stasis due to qi deficiency is the main pathogenesis of COPD.