明胶／纳米SiO2复合膜的体外抑菌试验

Bacteriostatic Test in vitro of the Gelatin/Nano-SiO_2 Composite Membrane

本实验测定了明胶、纳米SiO2、明胶/纳米SiO2复合膜对6种供试菌的抑菌效果,结果表明,明胶不具有抑菌作用;纳米SiO2对供试菌具有较好的抑菌效果;20种明胶/纳米SiO2复合膜材料中,有11种复合膜对供试菌具有较强的抑菌效果。用琼脂平板稀释法测定了具有较强抑菌作用复合膜的最低抑菌浓度(MIC),结果表明,最低抑菌浓度因膜的配比和菌种类型的不同而有所差异,为16.0mg/mL^256.0mg/mL。复合膜对蜡样芽孢杆菌的最低抑菌浓度(MIC)最大(256.0mg/mL),而对其他供试菌相对较低,为64.0mg/mL^128.0mg/mL。

The paper studied antibacterial effects in vitro of gelatin, nano-SiO2 and gelatin/nano-SiO2 composite membranes on 6 kinds of bacteria. The results indicated that gelatin had no antibacterial effect; nano-SiO2 had antibacterial effect; 11 out of 20 kinds of gelatin/nano-SiO2 composite membranes had strong antibacterial effects. Their minimal inhibitory concentrations （MICs） were also tested using the method of plate dilution, and the results indicated that they had different MICs because of different membranous formula and different bacteria. There were differences of MICs for different bacteria. For Bacillus cereu, MIC was 256.0 mg/mL; but for other bacteria, MICs were mainly 64.0 mg/mL-128.0 mg/mL.