某些有机硅及2-三丁基锡二茂铁衍生物的合成及表征

Synthesis of Organosilylferrocene and 2-(Tributyltin)-ferrocene Derivatives

由N，N-二甲氨甲基二茂铁（I）单锂化后与三甲基氯硅烷（Me3SiCl）反应，合成了2－（三甲硅基）二甲氨甲基二茂铁（Ⅱ）；Ⅱ再单锂化后与Me3SiCl反应得到了2，5-二（三甲硅基）二甲氨甲基二茂铁（Ⅲ）；单锂化的I与Me2SiCl2反应得到了双-［2－（二甲氨甲基）二茂铁基」二甲基硅烷（N）；双锂化I与二倍量的Me3SiCl反应得到2，1'-二（三甲硅基）二甲氨甲基二茂铁（V）．由碘化［2－（三丁基锡）三甲铵甲基二茂铁］分别与醇盐、酚盐、胺、邻苯二甲酰亚胺等亲核试剂反应，得到10个2－（三丁基锡）二茂铁衍生物．化合物经元素分析、1HNMR、IR和质谱表征．

N, N-Dimethylaminomethylferrocene (Ⅰ) was lithiated to the monolithi0 com-pound, which was then reacted with an equim0lar trimethylchlor0silicane to form 2-(trimethylsilyl) dimethylaminomethylferrocene (Ⅱ). When the monolithiated E was con-densed with trimethylchl0r0silicane, 2, 5-di (trimethylsilyl) dimethylaminomethylferrocene(Ⅲ) was obtained. The m0n0lithiated Ⅰ was allowed to react with half-molar dimethyldich-lorosilicane to yield bis [2-(N, N-dimethylaminomethyl) ferrocenyl] dimethyl8ilicane (Ⅳ)-2, l'-Dilithiated Ⅰ was obtained by lithiating Ⅰ in the presence of N, N, N', N' -tetra-methyl ethylene diamine (TMEDA ) and then condensed with double molartrimethylchlorosilicane to give 2, 1' -bis (trimethylsilyl)dimethylamin0met (Ⅴ).The structure of pr0ducts Ⅱ- Ⅴ were confirmed by elemental analysis, 1H NMR and MS.The methi0dide of 2-(tributyltin)dimethylaminometh was allowed to react with anumber of nucleophiles: sodium methoxide, sodium ethoxide, sodium phenolate, substitutedphenolates, piperidine, aniline, N-methylaniline and o-C6H4(CO)2NK. Ten new 2-(tributyltin)ferrocene derivatives were obtained and the structures of the ten products were de-termined by elemental analysis, IR and 1H NMR.