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B族I型清道夫受体的研究进展 被引量：1

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摘要 清道夫受体（scavenger receptor，SR）是一种细胞表面的糖蛋白，具有广泛的配基识别谱。20世纪70年代，Brown和Go1．dstein等通过实验发现一种可以和氧化低密度脂蛋白结合的AcLDL受体，因其可以和多种配体结合，并且参与机体免疫功能，故将其命名为清道夫受体。其中，B族Ⅰ型清道夫受体（SR—BI）是第一个在分子水平上得到证实的高密度脂蛋白（HDL）受体，参与并介导了胆固醇的逆向转运过程，而且还具有多种重要的生理功能。
作者 凌生林 付勇 廖斌
机构地区 泸州医学院附属医院心胸外科
出处 《泸州医学院学报》 2008年第5期580-582,共3页 Journal of Luzhou Medical College
关键词 B族Ⅰ型清道夫受体 receptor 高密度脂蛋白 机体免疫功能 LDL受体 细胞表面 蛋白结合 配体结合
分类号 R543.5 [医药卫生—心血管疾病] R392 [医药卫生—免疫学]
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参考文献21

  • 1Yancey PG, Bormlck AE ,Kellner Weibel G, et al.Importance of diferent path ways of cellular cholesterol efflux[J]. Anerioscler Thromb Vasc Biol, 2003;23:712
  • 2Vinals M,Xu S,Vasile E,et al.Identification ofthe N-linked glycosylation sites on the high density lipoprotein (HDL) receptor SIK-B I and assessment of their effects on HDL binding and selective lipid uptake [J]J Biol Chem, 2003 ; 278(7) : 5325
  • 3Yinan Peng,Wendy Akmentin,Margery A.Scavenger receptot BI (SIL-B1)clustered on microvillar extensions suggests that this plasma membrane domain is a way station for cholesterol traficking between cells and high-density lipoprotein[J].Mol Biol Cell, 2004; 15(1) : 384
  • 4Rhainds D.Brissette I .The role of scavenger receptor class B type I (SR-B1)inlipid traficking (defining the rules for lipid traders)[J].Int J Biochem Cell Bi-al,2004;36:39
  • 5Febbraio M,Hajjar DP,Silverstein RL.CD36:a class B scavenger receptor involved in an giogenesis atheroscleosis, inflammation an d lipid metobolism[J].Clin Invest,2001;108 (6) : 785
  • 6Ikemoto M.Identification of a PDZ-domain-containing protein that interacts with the scavenger receptor class B type Ⅰ[J],Proc Natl Acad sci USA,2000;97(12):6538
  • 7Liu B, Krieger M. Highly purified scavenger receptor class B, type Ⅰ reconstituted into phosphatidylcholine/cholesterol liposomes mediates high affinity high density lipoprotein binding and selective lipid uptake[J]. Biol Chem,2002;277: 3412S
  • 8GuX, Trigatti B ,Xu S, et al.The efficient cellular uptake of high density lipoprotein lipids via scavenger receptor class B type 1 requires not only receptor .-reed iated surface binding but also receptor specific id hamster mediated by its extraeclular domain[J].Biol Chem, 1998;273 : 26338
  • 9Rodrigueza Wv,Thuahnai ST,Temel R.E,et al.Mec hanism of scavenger receptor class B type 1-mediated selective uptake of cholesteryl esters from high density lipoprotein to adrenal cels[J].Biol Chem,1999;274:20344
  • 10Silver DL,Wang N, rau AR..Defective HDL particle uptake in ob/0b hepatecytes causes decreased recycling, degradation o and selective lipid uptake[J].Clin Invest, 2000; 105 : 151

二级参考文献28

  • 1蒋兆彦,韩天权,所广军,袁作彪,姜志宏,商俊,蔡杏兴,Gsta Eggertsen,Curt Einarsson,张圣道.胆固醇结石病人肝脏胆小管侧膜ATP基因表达差异的研究[J].外科理论与实践,2005,10(1):61-65. 被引量：24
  • 2张圣道,韩天权.执着追求胆石病的预防[J].外科理论与实践,2005,10(4):299-300. 被引量：4
  • 3傅培彬 张圣道.以胆石剖面结构及化学成分为基础的胆石分类法[J].中华外科杂志,1984,22(5):258-258.
  • 4Schreyer SA, Wilson DL, LeBoeuf RL. C57BL/6 mice fed high fat diets as models for diabetes-accelerated atherosclerosis[J]. Atherosclerosis,1998; 136:17-24.
  • 5Marchesini G,Brizi M,Bianchi G,et al . Nonalcoholic fatty liver disease a feature of the metabolic syndrome[J].Diabetes,2001;50:1844-50.
  • 6Marchesisni G,Bugianesi E,Gorlani G,et al.Nonalcoholic fatty liver,steatohepatitis,and the metabolic syndrome[J].Hepatology,2003;37:917-23.
  • 7范建高 曾民德 王均溶 等.上海市机关职工脂肪肝流行病学研究[J].中华流行病学研究,1998,19(1):409-11.
  • 8Kozarsky KF, Donahee MH, Glick JM, et al . Gene transfer and hepatic overexpression of the HDL receptor SR-B1 reduces atherosclerosis in the cholesterol-fed LDL receptor-deficient mouse[J].Arterioscler Thromb Vasc Biol,2000; 20:721-7.
  • 9Braun A, Trigatti BL, Post MJ, et al . Loss of SR-B1 expression leads to the early onset of occlusive atherosclerotic coronary artery disease, severe cardiac dysfunction, and premature death in apolipoprotein E-deficient mice[J]. Circ Res,2002;90:270-6.
  • 10An Y, Albers TJ. Glucose regulates the transcription of human genes relevant to HDL metabolism responsive elements for peroxisome proliferator-activated receptor are involved in the regulation of phospholipid transfer protein[J]. Diabetes,2001;50: 1851-6.

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泸州医学院学报
2008年 第5期

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