三维适形放射治疗局限性骨转移癌的止痛效果

RESULT OF THREE-DIMENSIONAL CONFORMAL RADIOTHERAPY FOR LIMITATION BONE METASTATIC CANCER IN PAIN ALLEVIATION

目的：分析三维适形放射治疗对局限性骨转移癌的止痛作用方法：全组52例，年龄48～75岁。非小细胞肺癌17例、乳腺癌15例、前列腺癌和肾癌各6例，直肠癌5例和3例为甲状腺癌转移。采用三维适形放疗，根据CT显示病变范围设定临床靶区，设5～6个共面照射野，根据剂量分布决定每个照射野的权重。中位剂量40Gy／8次，（平均35Gy-45Gy／7—10次）。治疗期间配合适量激素。结果：止痛效果明显，总有效率达100％。截止2007年2月，有随访结果的38例，其中18例生存1年，9例存活2年，6例存活3年，有5例存活4年健在。结论：三维适形照射技术对局限性骨转移癌不仅有肯定的止痛效果，而且对控制病变的发展同样是一种较为理想的治疗方法。

Objective： To analyze the effect of three-dimensional conformal radiotherapy on bone metastatic cancer pain alleviation. Methods ： 52 cases aged from 48 to 75, including 17 cases of non-small cell lung cancer,15 cases of breast cancer, 6 cases of prostate and kidney cancer, rectum cancer 5 cases and thyroid cancer 3 cases. Three-dimensional eonformal radiotherapy was used to treat the patients with a median dose of 40 Gy/8 times （35Gy-45Gy）/7-10 frequency. Results： Pain relief rate was 100%. Till February 2007, among the 38 follow-up patients, 18 cases survived 1 year, 9 cases survived 2 years,6 cases survived 3 years and 5 cases survived 4 years and still alive. Conclusion ： Three-dimensional conformal radiotherapy is an effective treatment method for bone metastatic cancer.