摘要
为研究阿米卡星脂质体的临床疗效,对110例被诊断为患猪肺疫(猪巴氏杆菌病)的仔猪进行了疗效试验。将患猪随机分为3组,空白对照组肌肉注射生理盐水;药物对照组肌肉注射阿米卡星,剂量为7.5mg/kg,每天用药2次,连用5d;试验药物组肌注阿米卡星脂质体,剂量为5.0mg/kg,每天用药1次,连用3d。结果表明,阿米卡星脂质体组治愈率和有效率分别为70.0%和76.0%,疗效显著高于药物对照组(P<0.01)。
110 pigs infected with Pasteurella multocida were tested in order to study curative effect of liposomal amikacin. The pigs were divided into 3 groups. The pigs in blank control group were administered with physiological saline, the pigs in drug control group were administered with amikacin for 5 days （7.5 mg/kg,2 times a day）, and the pigs in test group were administered with liposomal amikacin for 3 days（5.0 mg/kg, once a day）. The administration ways were all muscular injection. The results showed that the cure rate and effective rate in test group were 70.0% and 76.0%, respectively,which were significantly better than that in the control groups （P 〈0.01）.
出处
《动物医学进展》
CSCD
2008年第10期28-30,共3页
Progress In Veterinary Medicine
基金
湖南省教育厅资助项目(01C130)
关键词
阿米卡星脂质体
猪肺疫
疗效
liposomal amikacin
pig pasteurellosis
curative effect
