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苯并(a)芘暴露引起黑鲷肝、脾、肠组织病理变化 被引量:9

Histopathological Changes of Liver,Spleen and Small Intestines in Sparus macrocephalus Exposed to Benzo(a)payrene
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摘要 研究了黑鲷暴露于不同浓度的苯并(a)芘水体中,其肝、脾、肠等内脏组织的病理变化.观察结果表明:黑鲷较长时间暴露于含有苯并(a)芘的水体中,其肝、脾、肠等内脏器官组织结构受到不同程度的损害,如:肝细胞核肿胀,肝窦扩张,水样变性;脾窦扩张,淤血,空泡化;肠绒毛紊乱,杯状细胞增多.并且这3种组织随着暴露时间的延长,损伤程度日益严重.因此,海洋鱼类的组织病理变化可作为有机污染物的直接生物标记. In this paper, Sparus macrocephalus was exposed to waterbrone benzo (a) payrene at variety concentrations. Then the histopathological changes of the liver, spleen and intestines were studied. The result revealed that the histological structure in liver, spleen and intestines of Sparus macrocephalus were damfilled with blood, and there was vacuolation in spleen; intestinal villi were fouled-up, goblet cell manifolded. The severity extent of such lesions was dependent on the exposure time in the structure change of the three organs. So the histopathological changes in marine fishes can be used as direct biomarker for assessment of biological effects of organic contaminants.
出处 《集美大学学报(自然科学版)》 CAS 2008年第4期309-314,共6页 Journal of Jimei University:Natural Science
基金 国家自然科学青年基金资助项目(40106012) 国家自然科学基金资助项目(40476048)
关键词 苯并(A)芘 黑鲷 显微结构 benzo (a) payrene Sparus macrocephalus liver spleen intestines microstructure
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