双籽藤黄茎皮化学成分的研究

Chemical constituents from barks of Garcinia tetralata

目的：研究双籽藤黄Garcinia tetralata茎皮的化学成分。方法：采用硅胶、ODS柱色谱等方法进行分离纯化，根据理化性质及波谱数据鉴定化合物的结构。结果：从双籽藤黄95％乙醇提取物的氯仿萃取层中分离得到10个化合物，分别鉴定为1，7-二羟基[口山]酮（1），buchanaxanthone（2），garciniaxanthone H（3），1，2，5．-三羟基[口山]酮（4），subelliptenone H（5），6-deoxyisojacreubin（6），6-deoxyjacreubin（7），subelliptenone G（8），苔色酸甲酯（9）和β-谷甾醇（10）。结论：化合物1～10均为首次从该种植物中分离得到，化合物9为首次从该属植物中分离得到。

Objective： To study the chemical constituents of the barks of Garcinia tetralata. Method： Compounds were isolated and purified repeatedly by silica gel and ODS column chromatography and their chemical structures were elucidated by their physieoehemical properties and spectral data analysis. Result： Ten compounds were obtained and identified as 1, 7-dlhydroxyxanthone （1）, buchanaxanthone （2）, garciniaxanthone H （3）, 1, 2, 5-trihydroxyxanthone （4）, subelliptenone H （5）, 6-desoxyjaeareubin （6）, 6-deoxyisojaereubin （7）, subelliptenone G （8）, methyl orsellinate （9） and β-sitosterol （10）. Conclusion： Compounds 1-10 were isolated from this plant and compound 9 was obtained from the genus Garcinia for the first time.