哮喘豚鼠结状神经节、脊神经节和中枢内神经激肽A含量变化

Alteration of neuokinin A level in the primary afferent system and central nervous system of asthmatic guinea pig

应用放射免疫分析方法，检测１６只哮喘鼠一级传入系统和中枢内神经激肽Ａ（ＮＫＡ）的水平。与正常对照组（结状神经节６２８２±１１．０９ｐｇ／ｇｗ．ｗ，Ｃ７～Ｃ８段脊神经节５３．７８±１２．６３，Ｔ１～Ｔ２段脊神经节５４．２３±１９．０８，Ｔ３～Ｔ５段脊神经节５０．５３±１４．２３ｐｇ／ｇｗ．ｗ，Ｃ７～Ｔ５段脊髓后角４５．８６±１９．５６，孤束核５５．２７±１９．６８ｇｐ／ｇ．ｗ．ｗ．

The neurokinin A (NKA) level in the primary afferent system and central nervous system in asthmatic guinea pigs were measured by means of rallioimmunoassay. The results showed that compared with the contral group the NKA level was much higher in asthmatic group. The results indicated that NKA in the primary afferent system and central nervous system might be involved in the pathogenesis of asthma.