复发性口腔溃疡与甲状腺激素水平关系

Relationship of recurrent oral ulcer and serum level of thyroid hormones

本文用放射免疫分析法对刀例各病期的复发性口腔溃疡（ROU）患者和60例正常人血清甲状腺激素含量进行了检测和分析，结果如下：①ROU患者各期的血清FT4和FT3含量均低于正常人（P＜0．05，P＜001）；溃疡期含量最低，较初发期显著降低（P＜0．01）；愈合期、间歇期较溃疡期逐渐回升（P＜0．05，P＜0．01）旭间歇期含量仍低于初发期（P＜0．01和P＜0.05）。②ROU患者初发期的血清rT3含量高于正常人的含量（P＜0．01）；溃疡期、愈合期和间歇期血清rT3含量逐渐降低，但3期的含量与正常人含量无显著差异。③ROU患者各期血清TSH含量与正常人比较及各病期之间含量比较均无显著差异。结果表明ROU与血清甲状腺激素之间存在着密切而复杂的内在联系。

The serum thyroid hormones of 70 recurrent oral ulcer (ROU) patients and 60 normal persons were determined by radioimmunoassay. The results showed thats (1) Both FT4 and FT3 serum contens of any stage of ROU patients were lower than normal value (P< 0.05,p<0.01). The value at ulcerating stage were the lowest and the valueat healing and resting stages were a bit higher. However the value at resting stage were lower than that of beginning stage(p<0.01, P<0.05). (2) rT3 serum content of ROU patients at beginning stage was higher than that of normal persons(p<0.01), and that of the other stages were lower than beginning stage,but had not much difference from that of the normal persons.(3) TSH serum content at any stage had on significant difference from normal persons nor from each other. These results suggested that ROU may have complex intrinsic relatiollship with serum contents of thyroid hormones.