九种护肝中药抗脂质过氧化作用的研究

Studies on the Antilipid Peroxidation of Nine Sorts of Chinese Herbal Medicines with the Funcition of Protecting Liver

本文测定了丹参、田基黄、过路黄、野菊花、白芍、黄芩、女贞子、华紫珠、败酱草九种护肝中药对大鼠离体肝脏脂质过氧化的影响,发现受试药物均有抑制作用,且呈量效关系。上述结果表明,该组中药是天然抗氧化剂,其抗氧化作用可能是它们护肝及其他功效的现代药理学基础之一。

The antilipid peroxidation of nine sorts of Chinese herbal medicines with the function of protecting liver. including Salivia miltiorrhiza, Hypericum japonicum, Scutellaria baicalensis , Callicarpa cathayana, Chrysanthemum indicum, Paeonia latiflora, Lysimachia christinae, Ligustrum lucidum (Ll), Patrinia villosa (Pv) on hepatic homogenate of rat were tested. It was found that all tested medicines showed inhibition with dose-effect relationship, the inhibitory rate of Ll and Pv were lower than the other's. All results showed that these Chinese herbal medicines have strong antilipid peroxidation and are natural oxidation inhibitor. It was suggested that their function of protecting liver and others have relationship with the antioxidation.