摘要
目的研究鲍曼不动杆菌的感染分布及对常见抗生素的敏感性。方法采用回顾性方法统计分析324株鲍曼不动杆菌的标本来源、感染科室分布及耐药状况。结果324株鲍曼不动杆菌有246株来自痰液(占75.9%),来源于咽拭子及伤口分泌物的分别为28株(8.6%)和22株(6.8%),鲍曼不动杆菌的感染科室分别为呼吸内科占95株(29.3%)、重症监护病房(ICU)占52株(16.0%)、血液内科占49株(15.1%)。药敏结果显示,鲍曼不动杆菌对β-内酰胺类、氨基糖苷类、喹诺酮类均有较高的耐药性,而对碳青酶烯类、β-内酰胺类及含酶抑制剂复合药物较为敏感,其中最敏感的是亚胺培南93.5%,其次是美洛培南86.4%。结论鲍曼不动杆菌临床分离株多来自于痰液标本和呼吸科病房,并对多种抗菌药物的耐药率较高,临床应加强对鲍曼不动杆菌耐药性的监控并防治耐药菌株的传播流行。
Objective To investigate the distribution and drug resistance of clinical Acinetobacter baumannil isolates.Methods A statistic analysis for specimen sources, distribution departments and drug resistance of the 324 isolates was conducted in retrospective manner.Rebaits Among 324 isolates,246 (75.9%) came from sputum,28(8.6% ) from throat mucus and 22(6.8% ) from wound secretion respectively. The most strains from respiratory department, accounting for 29.3% (95 strains). 16.0% (52 strains) and 15.1% (49 strains) from blood department and ICU respectively. The Aeinetobaeter baumannil were resist to the β-laetamases, aminoglyeosides, fluomqninolones antibiotics. The sensitive rates to earbapenem were rather high, accounting for 93.5 % and 86.4% to lmipenem and Meropenem respectively. Conclusion Clinical isolates of Aeinetobaeter baumannil came from the sputum and respiratory department mainly and their resistant rates were rather high. We should pay more attention to the surveillance of antimicrobial resistance of Acinetobaeter baumannil in clinics and prevent transmission and epidemic of their resistance strains.
出处
《中国实验诊断学》
2008年第10期1299-1300,共2页
Chinese Journal of Laboratory Diagnosis
关键词
鲍曼不动杆菌
耐药性
抗菌药物
Acinetobacter baumannil
Antibiotic
Drug resistance