摘要
目的：研究清异颗粒的制备及质量控制。方法：采用薄层色谱法（TCL）对清异颗粒中黄芪、当归等进行定性鉴别;采用高效液相色谱法（HPLC）测定清异颗粒中阿魏酸的含量。结果：TCL鉴别能明显检出黄芪、白术、当归,分离度良好;HPLC法测定本品中阿魏酸的含量为3.217 1～3.876 4 mg.g^-1;阿魏酸在0.021 2～0.988 8μg范围内呈良好线性关系,r=0.999 9,平均回收率为100.71%（n=6）,RSD为1.26%。结论：质量控制方法简便快速,准确可靠,重现性好,适用于清异颗粒的质量控制。
Objective： To study the preparation and quality control of Qingyi granules. Method： TLC were used in the qualitative analysis; HPLC were used in the quantitative analysis. Results：Radix Astragali, Rhizoma Astractylodis macrocephalae and Radix Angelicae sinensis were detected by means of TLC methed. The ferulic acid - a common component of Radix Codonopsis, Radix Angelicae sinensis and Herb Oldenlandia was determined by HPLC. Conclusion： TLC and HPLC method can be used in the quality control of Qingyi granules.
出处
《药学与临床研究》
2008年第5期367-369,共3页
Pharmaceutical and Clinical Research
